Journal

38. Expansion of artificial intelligence for genome editing
Heesoo Uhm , Sangsu Bae
2025, Nature Structural & Molecular Biology, 32(12), 2380-2382, https://doi.org/10.1038/s41594-025-01722-2 Link
37. Pressurized intraperitoneal aerosol chemotherapy enhances cisplatin efficacy in colorectal cancer organoids
Soon-Chan Kim , Shin Ae Lee , Min Jung Kim , Young-Kyoung Shin , Hee Seung Kim , Ja-Lok Ku , Seung-Yong Jeong , Ji Won Park
2025, Scientific Reports, , , https://doi.org/10.1038/s41598-025-27866-1
36. Systematic growth factor profiling platform for 3D tumor models reveals estradiol-responsive cellular mechanisms of immunotherapy resistance
Kwanghwan Lee , Minsung Kim , Si On Lim , Dong-Ju Shin , Yun Shin , Jung-Joo Choi , Maria Lee* , Hyun Ju Kang* , Jeong-Won Lee* , Jin-Ku Lee*
2025, Biofabrication, 18(1), , 10.1088/1758-5090/ae26cc. Link
35. Integrative multi-omics of matched primary and liver metastatic colorectal cancer organoids identifies putative molecular targets
Chae-Young Kim , Soon-Chan Kim , Rumi Shin , Min Jung Kim , Seung-Yong Jeong , Ja-Lok Ku , Ji Won Park
2025, Translational Oncology, , , https://doi.org/10.1016/j.tranon.2025.102592
34. CABIN1 peptide effectively targets MEF2D-fusion protein in B-cell precursor acute lymphoblastic leukemia
Subin Cha , Sangho Lee , Han-Teo Lee , Hyonchol Jang , Hong-Duk Youn
2025, Signal Transduction and Targeted Therapy, 10(1), , 10.1038/s41392-025-02397-3
33. PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
Shao Wei Hu , Sohyang Jeong , Luoying Jiang , Hansol Koo , Sangsu Bae , Sang-Yeon Lee , Yilai Shu
2025, Nature communications, 16(1), , https://doi.org/10.1038/s41467-025-62562-8
32. AI-generated MLH1 small binder improves prime editing efficiency
Ju-Chan Park , Heesoo Uhm , Yong-Woo Kim , Ye Eun Oh , Jang Hyeon Lee , Jiyun Yang , Kyoungmi Kim , Sangsu Bae
2025, Cell, 188(21), , https://doi.org/10.1016/j.cell.2025.07.010
31. A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease
Keewon Sung , Youngri Jung , Nahye Kim , Yong-Woo Kim , Hyongbum Henry Kim , Seong Keun Kim , Sangsu Bae
2025, Nucleic acids research, 53(12), , https://doi.org/10.1093/nar/gkaf535
30. Bystander editing by adenine base editors impairs vision restoration in a mouse model of Leber congenital amaurosis
Seok-Hoon Lee , Jun Wu , Dongjoon Im , Gue-ho Hwang , You Kyeong Jeong , Hui Jiang , Seok Jae Lee , Dong Hyun Jo , William A. Goddard III , Jeong Hun Kim , Sangsu Bae
2025, Molecular therapy Methods & clinical development, 33(2), , https://doi.org/10.1016/j.omtm.2025.101461
29. The Role of ASXL1, SRSF2, and EZH2 Mutations in Chromatin Dysregulation of Myelodysplastic Syndromes and Acute Myeloid Leukemia
Hosang Yu , Junshik Hong , Dong-Yeop Shin , Chul-Hwan Lee
2025, Leukemia, , , https://doi.org/10.1038/s41375-025-02657-9
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